Breast tumors and parotid tumors connection

Language: English German. Parotid gland metastasis in breast cancer is extremely rare, and only 14 cases have been reported between and A year-old female patient was diagnosed with invasive lobular carcinoma of the left breast. Although clinical staging was T1N3M1 stage IV , the tumor experienced a complete response to chemotherapy. We therefore performed a mastectomy followed by radiotherapy, and continued administration of trastuzumab.

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Potential link between breast cancer genes, salivary gland cancer

Potential link between breast cancer genes, salivary gland cancer -- ScienceDaily

The risk of developing cancer in a salivary gland might be higher in people with mutations in either of two genes associated with breast and ovarian cancer, according to a new study by researchers at The Ohio State University Comprehensive Cancer Center -- Arthur G. James Cancer Hospital and Richard J. Although salivary gland cancer is rare, this retrospective study suggests it occurs 17 times more often in people with inherited mutations in genes called BRCA1 and BRCA2, than those in the general population. Schuller, MD, and Carole H. It is well known that women who inherit mutations in either of the two genes have a higher risk of breast and ovarian cancer than women without the mutation; men with the mutations are at higher risk of breast cancer. The two mutated genes are also linked to prostate, pancreatic and other cancers.
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Parotid Gland Metastasis of Breast Cancer: Case Report and Review of the Literature

James Cancer Hospital and Richard J. It is well known that women who inherit mutations in either of the two genes have a higher risk of breast and ovarian cancer than women without the mutation; men with the mutations are also at higher risk of breast cancer. In addition, the two mutated genes are linked to prostate, pancreatic, and other cancers. Cancers of the salivary glands are rare in the United States, with about three cases occurring annually per , adults in the general population 0. This retrospective study suggests it occurs 17 times more often in people with inherited mutations in the BRCA1 and BRCA2 genes than those in the general population.
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This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited. Salivary, mammary and prostate glands are sex hormone-dependent organs sharing common aspects in structure, hormonal responsiveness and tumor histopathology. Salivary tumors especially the malignant types are not as frequent as mammary and prostate neoplasias. Hence, prognosis of some salivary tumors is not always efficient.
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